3 consecutive miscarriages


1 Posts
Reply Posted on: Jan 25, 2013 at 12:28pm
Hi Dr. Braverman,
I just turned 36 and have had 3 consecutive miscarriages in the last 11 months. The first was a missed miscarriage at 9 weeks; no heartbeat was detected at ultrasound and it seemed that growth stopped around 6 1/2 weeks. MVA procedure was performed and testing of the products of conception revealed Trisomny 10. We had an ultrasound at 8 weeks for the second pregnancy which revealed low fetal heartbeat (no exact number was ever given to us) and we were told to come back in one week. Before the end of that week I started bleeding and miscarried at home. After the 2nd loss, I had an RPL blood work up and my husband had a karyotype done; the Dr. said everything was normal. With the third pregnancy we had an ultrasound at 6 weeks and I was measuring on track but there was a low fetal heartbeat (again we were not given a number). When we returned for the 8 week ultrasound no fetal heartbeat was detected. I just had a D&C for the 3rd miscarriage and we are awaiting the results from the chromosomal testing.
After this last miscarriage I changed doctors because I felt my previous doctor was not aggressive enough in trying to find out why this was happening. I requested a copy of my medical records from the old doctor and was surprised to see in my file that I actually tested positive for 2 copies of the C677T mutation. There was also a note on the results for Protein C Activity that said "attachment to follow" although there is no attachment. Now that I have a new doctor I would like to be as pro-active as possible about finding out why we continue to have early losses. Do you think the fact that I am homozygous for the C677T mutation could be a reason for these losses? Are there additional tests you think I should explore with my new doctor?
Thank you, in advance, for your time and feedback.

Dr. Braverman

2026 Posts
RE: 3 consecutive miscarriages Posted on: Jan 25, 2013 at 2:29pm
I am very sorry for your losses. Yes the MTHFR can be the cause of your issues but I consider that unlikely , as there are quite a few other tests tthat should be done. I would be more than happy to guide you with this. YOu should call my office and they can schedule a free 10 minute chat so I can get a better idea of what you need.
Dr. Jeffrey Braverman MD FACOG
Medical Director
Braverman Reproductive Immunology P.C.