Adenomyosis - 2 questions

TKK

3 Posts
Reply Posted on: May 28, 2014 at 10:37pm
Dear Dr Braverman,

I have booked a consult with you which is coming up shortly. In the meanwhile I am trying to research as much beforehand so that our consult can be as efficient and beneficial as possible.

I have two generic questions regarding adenomyosis suppression for which I have been unable to find internet answers (I am aware that this is a symptom of immune issues and realise that immune treatment is required in addition to the adeno suppression).

1) why is the typical suppression treatment length 12 weeks? Why is 12 any better than 6, 8 or 10 weeks?

2) how long do the benefits of the suppression last? Is it just until the next transfer and (if that fails) the period that follows that. Does the full adenomyosis return once you have that next bleed? Would a further 12 weeks of suppression therefore be recommended before attempting a second transfer or do the benefits of the first suppression period extend to subsequent transfers.

thankyou
TKK

Dr. Braverman

2026 Posts
RE: Adenomyosis - 2 questions Posted on: Jun 6, 2014 at 5:09am
There is no data on "suppressing" adenomyosis, all of the treatments recommended are speculation that is why you see no uniformity in results . Endometriosis should be excised but adeno being inside the uterine musculature can not so attempts are made to "suppress" but how do you know if you have done so since you can not surgically remove the uterus to look? What is it that is being suppressed. There are studies looking at integrins with endo and "resetting" the endometriuim with 12 weeks of lupron and increasing the integrin levels, i have had similar success with 5 days of femara.
Dr. Jeffrey Braverman MD FACOG
Medical Director
Braverman Reproductive Immunology P.C.