adenomyosis, chronic endometritis, endo

victory

9 Posts
Reply adenomyosis, chronic endometritis, endo Posted on: Feb 5, 2011 at 4:29pm
I have been diagnosed with adenomyosis(1-2cm on left anterior uterus),chronic endometritis, endo. Have you seen patients with adenomyosis get pregnant with your treatments? Can G-CSF help with this? Anyway I am meeting you soon so looking forward to meeting you.

I have done antibiotic treatments for the above diagnosis.

Dr. Braverman

2026 Posts
Re: adenomyosis, chronic endometritis, endo Posted on: Feb 5, 2011 at 11:03pm
yes this can all be treated but 2 different diagnosis and treatments. The chronic endometritis requires long term antibiotics and the adenomyosis needs multiple treatments to lower inflammatory cytokines locally as well as immune cells that are activated by the adenomyosis and endometriosis. Look forward to meeting you.
Dr. Jeffrey Braverman MD FACOG
Medical Director
Braverman Reproductive Immunology P.C.

victory

9 Posts
Reply Re: adenomyosis, chronic endometritis, endo Posted on: Jul 7, 2011 at 5:38pm
Dr Braverman,

I have some questions that I thought of after the consult.

I explained to you that I have done treatment for chronic endometritis with uterine lavages, IV and oral antibiotics a few times and I still had FETs implantation failures. Can neupogen help with this issue?
Also my laparotomy report states that"the endometrium was extensively mottled with endometrial stippling consistent with chronic endometritis" Do you think the basal layer of the endometrium could have been affected and that is why I have implantation failure? I think you mentioned in another post that neupogen will not work if the basal layer is destroyed. What do you think of my situation?

Also you mentioned about multiple treatments to lower cytokines for adenomyosis and endo. What are they? Does that include neupogen, IVIG, lovenox. Anything else??

Thank you.

Dr. Braverman

2026 Posts
Re: adenomyosis, chronic endometritis, endo Posted on: Jul 10, 2011 at 5:47pm
No infection wont destroy the basalis cells, and you were adequately treated for infection regardless. Yes neupogen will help with the cytokine elevation. Remember the elevated cytokines cause the failure of the immune cells to tolerate the pregnancy but they themselves are not the problem. neupogen assists those same cells in generating immune tolerance regardless of the cytokine levels. But if not using nuepogen, then omega 3, antioxidants, prednisone all do an adequate job.
Dr. Jeffrey Braverman MD FACOG
Medical Director
Braverman Reproductive Immunology P.C.

miracle

9 Posts
Re: adenomyosis, chronic endometritis, endo Posted on: Sep 22, 2011 at 10:50am
I have been recommended for adenomyosis that it is better to do down regulate first 2-3 months with depot lupron before FET. Do you think neupogen alone will help with adenomyosis or chronic endometritis? Have you seen issues like mine get pregnant just with neupogen? I have consulted with you and all you recommend is neupogen. I also have viral issues which I need to take valtrex. Can I take neupogen with valtrex or its generic with FET?

Thank you.