Anti-H-Y

Kristen_tt

2 Posts
Reply Posted on: Jan 26, 2013 at 4:32pm
Could the presence of the H-Y antibodies cause a positive ANA result? Or are they likely unrelated?

Dr. Braverman

2026 Posts
RE: Anti-H-Y Posted on: Jan 26, 2013 at 7:58pm
any immune attack against the trophoblast or other paternally derived genetics can lead to cell destruction , release of nuclear material and anti nuclearl antibodies ANA. so yes it can cause a pos ANA we have seen patients convert to pos ANA during their pregnancies.
Dr. Jeffrey Braverman MD FACOG
Medical Director
Braverman Reproductive Immunology P.C.

Kristen_tt

2 Posts
Reply RE: Anti-H-Y Posted on: Jan 28, 2013 at 5:06am
Thank you. I have a history in which the h-y antibodies seem to be a strong possibility. That, coupled with my positive ANA test (early pg--in which another m/c seems imminent). Do you usually screen for the h-y antibodies when you suspect them or just treat in the future with prednisone, etc.? My provider and I are having a difficult time trying to figure out what tests need to be ordered to check for the h-y antibodies...

Dr. Braverman

2026 Posts
RE: Anti-H-Y Posted on: Jan 28, 2013 at 6:55am
There is no test currently for HY antibodies , we are working on this. These types of problems are best in the hands of those that can make a correct diagnosis before offering treatment. You can also do a full HLA panel to look for the presence of genes that can predispose to the HY antibody production. I would be happy to help you with this.
Dr. Jeffrey Braverman MD FACOG
Medical Director
Braverman Reproductive Immunology P.C.