DQ -Alpha Match


1 Posts
Reply Posted on: Feb 9, 2014 at 5:32pm
Hi,Are there any options for a couple with the following dq-alpha genotypes:Husband — 0501,0501
Wife — 0103,0501This is a total match, correct? Therefore, are the only options a gestational carrier or donor sperm? Or are there treatments that can be tried? Should further testing be done?My daughter and her husband have been dealing with infertility for several years. They are 31 and in good health overall.After failing to conceive on their own, they tried IUI a couple of times with no luck, then moved on to IVF/ICSI with a three-day transfer. She did two fresh cycles and one frozen. Each time, she had an initial positive beta test, but then lost the pregnancies before getting to the first ultrasound to detect a heartbeat. On her third IVF cycle, she got the furthest along, making it about 27 days post-transfer (although she started spotting at about day 20).Any recommendations on options they may have, other than a gestational surrogate or sperm donor?

Dr. Braverman

2026 Posts
RE: DQ -Alpha Match Posted on: Feb 9, 2014 at 9:12pm
Please read my blog on HLA ananlysis on my website. I think it will make it very clear how little significance there is to only doing DQalpha matching. Best would be for our daughter to fill out a consult request and we will arrange a free 10 minute chat wtih her.
Dr. Jeffrey Braverman MD FACOG
Medical Director
Braverman Reproductive Immunology P.C.