endometriosis, low morphology and embryo quality


1 Posts
Reply Posted on: Feb 18, 2015 at 3:00am
Hi Dr Braverman,My husband and I just had our first failed IVF/ICSI cycle. We had a great fertilization report on day 1 but things went downhil after that. Just for background, we had 10 Ret, 8 Mat, 7 Fert. Almost all the embryos had 10-20% fragmentation. (5) embryos arrested at 4-6 cell stage between day 2/3, (1) arrested at 16 cells between day 3/5, and then we had (1) morula on day 5.

My dr is saying the poor embryo quality is an egg issue which is scary because I'm only 29. I do have endometriosis but NOT endometriomas. Is it still possible for the endo to have affected my egg quality despite the absense of endometriomas? If so, is there anything I can do to help or am I destined for donor egg? My other question is at what point does paternal DNA start to influence the process? I have read day 3 but also when the embryo is 4-8 cells. (I ask because we had (4) embryos 5-6 cells on day 2 that didn't progress further). So, is it cellular dependent or day dependent? My husband has poor morphology so I'm trying to get a sense as to whether it really is bad eggs or if it could be something wrong with the sperm, or both.

Or perhaps there's nothing wrong with us and it was a bad protocol? How do you best distinguish what was responsible for the poor quality embryos?Thank you!

Dr. Braverman

2026 Posts
RE: endometriosis, low morphology and embryo quality Posted on: Feb 18, 2015 at 6:19am
I beleive in your case both the endometriosis (and you dont need an endometrioma for this to affect egg quality) and the sperm are playing a a part. I would start by getting "resective surgery" to remove the endometrioisis . This may significantly improve your egg quality. There are medicaitons and supplements your husband can go on to improve his sperm as well.
We offer this surgery for women around the world and you should consider coming here for us to help you.
Feel free to fill out a consultation request and we can schedule a free 10 minute chat.
Dr. Jeffrey Braverman MD FACOG
Medical Director
Braverman Reproductive Immunology P.C.