Foxp3 cells in uterus


4 Posts
Reply Posted on: Jul 6, 2014 at 5:13am
Dear Dr Braverman - in my uterine biopsy report there is a sentence: “Foxp3+ (regulatory) T-cells are present at approximately 0 per mm squared”. Is this something to be concerned about? the little I can find online tells me that it is. What can be done? I have high CD57 uNK at 30 per mm squared. I am alarmed at the lack of Foxp3+ T cells... my FS in Australia does not know anything about it. Do I need IVIG instead of intralipid? I am also on dexamethasone 2mg a day from day 1 of IVF cycle commencing, clexane and progesterone.

Thank you for your advice.

Dr. Braverman

2026 Posts
RE: Foxp3 cells in uterus Posted on: Jul 6, 2014 at 7:26am
I find the uterine biopsies to be of little value in making a diagnosis, the results by themselves give no true diagnosis. If you have been having problems I suggest you augment any uterine biopsy(which results are unreliable) and combine this with a complete blood workup . I would certianly never direct treatment based solely on this test (the suggestion here is that you do not have T Regulator cells in the uterine cavity , a conclusion there is no basis for).
Feel free to fill out a consutlation request from the website and we can schedule a ree 10 minute chat to review your case.
Dr. Jeffrey Braverman MD FACOG
Medical Director
Braverman Reproductive Immunology P.C.