Leukocyte Antibody Detection Panel


4 Posts
Reply Posted on: Apr 30, 2014 at 6:25pm
Dear Dr. Braverman,
I am curious about your current beliefs about the LAD panel. Do you feel the test is important and what treatment would you give to a patient with my results as below:

Flowcytometry: Negative

T cells (IgM) 7.7
T cells (IgG) 3.0
B cells (IgM) 21.4
B cells (IgG) 2.9

Thank you for your help. I appreciate it.

Dr. Braverman

2026 Posts
RE: Leukocyte Antibody Detection Panel Posted on: May 1, 2014 at 7:58am
The clinical history is more important, if you have never had a full term pregnancy you WILL not have any antibodies so in that case this test (the LAD ) is of no value. Understanding why you have HLA antibodies and what kind they are is very important and different in every case. We only look at specific anti HLA antibodies by testing and identfying them directly with a luminex test(the LAD is very non specific, see my blog about it) . Once I see patients offered LIT it usually means the center that is treating them does not have a good handle on the problem and you are most liklely not gettting the treatment you do need. See my Diagnostic Testing Page.
Dr. Jeffrey Braverman MD FACOG
Medical Director
Braverman Reproductive Immunology P.C.