Limited to 1 Embryo per Transfer?


1 Posts
Reply Posted on: Jun 5, 2014 at 3:00pm
When we were waiting for our DQ Alpha test results our RE said that even a partial match would mean that we should only ever transfer one embryo at a time. The reason they gave was because they think that the embryo makes the immune system flare up and attack it and so transfering 2 would make it flare up even more and attack even more aggressively.

We turned out to be a complete match.

Now that I am reading your website and finding out that RIs don't think of DQ Alpha matches in the same way as REs I still cannot get it out of my head that we should limit ourselves always to one embryo at transfer.

So my question is, if properly treated for underlying issues by an RI, should we be limited to transfering only 1 embryo because of the DQ Alpha match or could we transfer 2?

Thank you in advance.

Dr. Braverman

2026 Posts
RE: Limited to 1 Embryo per Transfer? Posted on: Jun 6, 2014 at 4:41am
Most of my pregnancies that I reported with complete DQ alpha mathcing(which by the way is not a diagnosis of anything but coincidence!) had 2 embryos transferred. I beleive there were 9 out of 10 patients. Need I say more. All of this rational about one embryo is really invalid speculation by someone with no knowledge of the immunologic mechanisms of embryo acceptance by the immune system. The only possibilty based on factual evidence and our theory of embryo acceptance(read my latest blog from ASRI) is that a good embryo could help a bad one . It is rather complex but has NOTHING to due with DQalpha molecules which are not ANYWHERE on the embryo it does not show up until much later in the pregnancy!, so how could it possibly affect early implantations? I suggest you get a correct diagnosis of your issues before placing in any embryos as based on the above you dont have one.
Dr. Jeffrey Braverman MD FACOG
Medical Director
Braverman Reproductive Immunology P.C.