Neupogen timing

CindyS

5 Posts
Reply Posted on: Jan 3, 2013 at 12:47pm
Hi Dr. Braverman,
I have a question re the timing of starting neupogen. I have had three cycles using neupogen starting at 2-3dpo (under care of an RE with neuopgen experience) and have been unsuccessful in getting pregnant. I have a history of falling pregnant easily (5 times so far within a month or two of trying) and the three cycles were monitored with good ovulation, great progesterone and no male factors.

My question is - can neupogen started that early interfere with implantation?

I have had one successful pregnancy using ivig, progesterone and lovenox however all these medications were administered after a positive pregnancy test and not before.

(PS, The decision to move to neupogen was made due to my success with ivig however I had numerous side effects and am no longer a good candidate for its use in the future.)

Thank you for your help,
CS

Dr. Braverman

2026 Posts
RE: Neupogen timing Posted on: Jan 3, 2013 at 3:27pm
No I dont think its the timing of the neupogen that is the problem. The question is whether you are getting the correct response and whether adjustments need to be made.
Dr. Jeffrey Braverman MD FACOG
Medical Director
Braverman Reproductive Immunology P.C.

CindyS

5 Posts
Reply RE: Neupogen timing Posted on: Jan 3, 2013 at 3:47pm
Hi Dr. Braverman,

Thank you so much for your quick response.

My doctor wants to run WBC counts and NKA tests after 7-10 on the Neupogen however since I get a BFN around that time they decided not to run the tests until I am successfully pregnant. I'm on neupogen for HLA issues, are there other monitoring tests that should be included as well for that diagnosis?

Should I insist on checking my levels next cycle before stopping the medication to make sure that the levels are sufficient or is it best to wait and test after falling pregnant (as the levels will likely change)?

Also, is it possible that I should start the Neupogen earlier in my cycle (before ovulation) to give the medicine more time to work before possible implanation?

Thank you again for your help.

CS

Dr. Braverman

2026 Posts
RE: Neupogen timing Posted on: Jan 3, 2013 at 4:02pm
which HLA issues are being treated, haplotypes or class 2 matching? I would draw the tests regardless of whether you are pregnant. May I ask which clinic is monitroing you? You can email me privately if you wish
[email][email protected][/email]
Dr. Jeffrey Braverman MD FACOG
Medical Director
Braverman Reproductive Immunology P.C.