neupogen wash

teenwolf

1 Posts
Reply Posted on: Jan 23, 2012 at 9:40pm
Hello,

I have now had 4 miscarriages with IVF single embryo transfers. 2 were chemical pregnancies and 2 made it to 8 weeks when the heart beat went away. The two that made it to 8 weeks were tested and determined normal male XY karyotype. The 4th miscarriage (chemical) was tested prior to transfer with CCS and was catagorized as a normal 5AA blast. I've always had chronic thin linings. Acupuncture has certainly helped, but hasn't completely fixed the problem. My E2 is always quite high (so I am absorbing it well) with little effect on my lining (we've tried estrace (oral and suppository), vivelle patches (least effective for me) and del estrogen IM shots (most effective) and of course daily baby aspirin over the years. Stims (creating natural estrogen) doesn't really seem to make a difference. This last cycle (chemical pregnancy), I was also following the Alan Beer clinic protocol and did 2 series of LIT to fix LADs (this worked and fixed my NK cells as well), humira (to correct for NK cells in lining and slight flux in TH1:TH2) and preventative IVIG before transfer. After this recent chemical pregnancy, my RE has suggested doing a Neupogen Uterine Wash. I was wondering how that fit in with other immunology treatments. I have heard that you should not do neupogen at the same time as IVIG but is this only when using neupogen subQ or is this for the wash as well? What about other immunology treatments such as humira? As with many others, I'm in a tough spot of trying to coordinate my western medical treatment (RE) with my alternative treatment (RI).

Also, my RE has suggested trying a "scratch test" which is a therapeutic biopsy prior to starting the next FET meds. Any thoughts/successes on this approach?

Thank you for your thoughts on this! I have heard tremendous things about the cutting edge ideas you bring to the table and the assistance you've given many couples to become and stay pregnant and truly appreciate any guidance you can provide me.

Thank you,
Tina

Dr. Braverman

2026 Posts
RE: neupogen wash Posted on: Jan 25, 2012 at 1:00am
there is no data on the use of IVIG with neupogen, we have treated several patients with both without adverse outcome. you may benefit from both a neupogen wash as well as the SQ.
I would be happy to go over your entire case with you and put together a coherent plan, we can work with your RE wherever you are and most accomodate the advice of our center.
Please feel free to call my office and schedule a telephone or skype consultation.
Dr. Jeffrey Braverman MD FACOG
Medical Director
Braverman Reproductive Immunology P.C.

Hadleigh

35 Posts
RE: neupogen wash Posted on: Jan 26, 2012 at 1:45pm
Hi Tina and/or Dr. Braverman.

Could you tell me what is the reason for a "scratch test" which is a therapeutic biopsy prior to starting FET meds? I have never heard of this before and wondering why it would be done.

Thanks.

Dr. Braverman

2026 Posts
RE: neupogen wash Posted on: Jan 26, 2012 at 9:00pm
It activates an enzyme that promotes implantation in the following cycle.
Dr. Jeffrey Braverman MD FACOG
Medical Director
Braverman Reproductive Immunology P.C.