partial dq alpha match

north

1 Posts
Reply Posted on: Jan 18, 2015 at 10:00pm
Hi Dr. Braverman,
My partner and I recently received our immune results back and I wanted to get your opinion on them.
I was initially tested in August 2014 and found to have elevated NK cells. Further testing revealed that we have a 06 dq beta match (we each have one of these), a 2.0 dq alpha match (we each have one of these), and we each have a DRB3 present (there's a couple numbers in front of this but they are different between us). Each of us also has one homozygous allele (me on HLA-B and my partner on HLA-C). [TPO antibodies are negative, thyroglobulin antibodies are negative, and antiphospholid antibodies are negative.]
Our doctor said that this profile qualifies as a "partial dq alpha match" and he said it would reduce our chances by 50% as only one in every two genetically normal embryos (even with donor eggs) could be successful.
We're currently faced with making some big decisions about which direction to go and are considering donor sperm versus our own sperm (while using donor eggs) in order to avoid further disappointment.
What's your sense of these results?
Thanks for your time,
north

Dr. Braverman

2026 Posts
RE: partial dq alpha match Posted on: Jan 19, 2015 at 6:34am
My opinion is that a Partial DQalpha match (which is not a diagnosis) in no way impairs implantation by any percentage and does not require donor sperm . There is clearly another diagnosis here that has not been made. My advice is to read my blog on HLA and then to schedule a free 10 minute consult with me so we can review your case . Simply fil out the consult form below.
Dr. Jeffrey Braverman MD FACOG
Medical Director
Braverman Reproductive Immunology P.C.