Positive ANA, no autoimmune diseases detected


1 Posts
Reply Posted on: Aug 12, 2012 at 6:55pm
I have been to a rheumatologist twice now for my positive ANA and no autoimmune diseases have been detected. My latest level was 1:640, which was an increase from a test taken a week ealier resulting in 1:320. I first dicovered a positive ANA 3 years ago which was 1:160 at the time. I have been trying to conceive for a little over a year and had 1 miscarriage after 5 weeks within this time. At this point everything else during my infertility workup is appearing okay and drs don't seem to feel the ANA is a problem, but I am concerned. Although they have no explanation for why my levels are high they feel it could have something to do with my maternal grandmother having rheumatoid arthritis.

In your experience, is it possible that there really is no underlying problem that is causing this fluctuating positive ANA? And in my case, is the positive ANA really not a concern in trying to conceive and having a healthy baby?

Thanks in advance for any insight!

Dr. Braverman

2026 Posts
RE: Positive ANA, no autoimmune diseases detected Posted on: Aug 12, 2012 at 7:39pm
Please see my video and blog on pos ANA and miscarraige. They are wrong just having a positive ANA even if no underlying autoimmune syndrome is identified is associated with early losses, this is most likely through complement activation when the ANA binds directly to the trophoblase. The good news is this is readily treatable.
Dr. Jeffrey Braverman MD FACOG
Medical Director
Braverman Reproductive Immunology P.C.