Question regarding IFN-g:IL10

LemonD

3 Posts
Reply Posted on: Nov 21, 2012 at 12:55pm
Dr Braverman,

I have difficulties with my lining being thin - reaches 4.8mm on a normal cycle with no TX, but on a medicated DE cycle with GCSF it reached 8.2mm which was encouraging but still resulted in a negative result.

i'm now revisiting my immune test results and have noticed that my IFN-g:IL10 were low at 4.7 (my TNF-a:IL10 was 16.0), I wondered if this could also be hindering my implantation success.

I would be grateful for your opinion and any suggestions.

Thank you so much.

Dr. Braverman

2026 Posts
RE: Question regarding IFN-g:IL10 Posted on: Nov 21, 2012 at 2:33pm
Yes that is low, as we have written about on our website, lack of inflammation may also lead to implantation failures. I would be happy to discuss your case with you in detail so I can get a better idea of all the issues. Feel free to call my office for a consult.
Dr. Jeffrey Braverman MD FACOG
Medical Director
Braverman Reproductive Immunology P.C.

LemonD

3 Posts
Reply RE: Question regarding IFN-g:IL10 Posted on: Dec 14, 2012 at 2:02pm
Dr Braverman,

if I was to have my IFN-g:IL10 retested and it's still low, could you give me an idea of treatment to encourage uterine inflammation, would you suggest hcg wash prior to transfer?

i need to have the GCSF infusion to give me a decent lining, so if you do suggest the hcg wash does this work alongside the GCSF?

Many thanks

Dr. Braverman

2026 Posts
RE: Question regarding IFN-g:IL10 Posted on: Dec 15, 2012 at 3:23pm
well , they would most likely do the same thing. so only one wash would be important i.e. the G-CSF. Also taking probiotics may help to raise these levels back to normal as well. Stay off antioxidants or fish oil if you are taking them.
Dr. Jeffrey Braverman MD FACOG
Medical Director
Braverman Reproductive Immunology P.C.

LemonD

3 Posts
Reply RE: Question regarding IFN-g:IL10 Posted on: Dec 21, 2012 at 11:38am
Dr Braverman,

i've had my IFN-g:IL10 restested in Athens, Greece and this time it's come back at 3,1 pg/mL (previously 4.7 Ratio when tested on the Chicago test - I think Athens use a different unit to test?).

is this still considered to be low, ie 3,1 pg/mL?

thank you.

Dr. Braverman

2026 Posts
RE: Question regarding IFN-g:IL10 Posted on: Dec 21, 2012 at 1:06pm
yes this is still low.
Dr. Jeffrey Braverman MD FACOG
Medical Director
Braverman Reproductive Immunology P.C.