RPL using oocyte donation


1 Posts
Reply Posted on: Jul 25, 2013 at 12:47pm
Dear Dr. Braverman,
I am 46 years old. I have 3 children from a previous marriage, all 3 pregnancies were normal. 2 years ago I began IVF with my current husbnad & failed. Because of my age, we moved on to the egg donation program at Hadassah hospital in conjuction with Reprofit clinic in the Czech republic. The first fresh embryo transplant in November 2012 was sucessful & resulted in a twin pregnancy. I miscarried at 5 weeks. Tests were performed & I was diagnosed with thrombophylia (factor V leiden & mthfr). I had a F.E.T. on a natural ovulation cycle in January 2013 which resulted in a singleton pregnancy, I took 40 mg. of clexane a day but ended up miscarrying in week 6. I decided to change donors & did a new fresh cycle in May 2013 which resulted in another twin pregnancy. I was on 60 mg. of clexane & miscarried once again after hearing 2 heartbeats in week 5.5. All my tests are normal with the exception of a high level of anti thyroid antibodies(over 1000). My thyroid has been functioning normally for the past few years, I take 150 mg. of eltroxin hormone a day. I do not have anti nuclear antibodies & my husband has a normal kariotype. A new protocol has been made for the next F.E.T. to include IVIG, clexane, dexamethasone & pregnyl. The treatment has been delayed a bit b/c at the moment I am apparently ovulating/menstruating at the same time (my last miscarriage was a month ago). The phsyician who is treating me at Hadassah is a Professor & head of the IVF unit. I have also consulted with Prof. Howard Carp of Sheba hospital who is known internationally for his work relating to RPL. I know they are both top notch doctors but I would still like to have another opinion from an expert in reproductive immunology. Thank you and Shalom.

Dr. Braverman

2026 Posts
RE: RPL using oocyte donation Posted on: Jul 25, 2013 at 1:29pm

I would be happy to assist you in what is most likley an immune related failure. Best would be to fill out a consult request on our site and schedule a SKYPE or telephone consultation with me.
I would suggest delaying any transfers until we can get our workup done.
Dr. Jeffrey Braverman MD FACOG
Medical Director
Braverman Reproductive Immunology P.C.