5 Posts
Reply Posted on: Nov 15, 2012 at 4:36am
Dear Dr Braverman,

Thanks so much for your answers and for taking out time to offer us all a lifeline.

I've just had my 5th fresh ICSI failure, this time with a massive cocktail of immune treatment including 40 mg prednisolone, neupogen, IVIg and intralipids. We're exploring next steps including supplements, and I might come back another time with specific immunology query.Your opinion on green supplements is of interest to me as I have high TNF (42) and have been taking powdered organic spirulina daily (in a smoothie with organic berries and organic whole milk), for a year and a half. In my view, the spirulina and and DHEA have helped to produce a substantial difference in my egg quantity/quality, going from two eggs last year to 12 eggs in last cycle. I am 39 years old.However, given my immune challenges, I would appreciate your opinion on spirulina based on the attached references.

One of the relevant articles (below), “the researchers found that spirulina increased the tumour-killing ability of NK cells and the interferon significantly. This activity was increased 1–2 weeks after administration of spirulina and the activity continued for 12–24 weeks even after spirulina supplementation had been stopped. “


Another said that immunostimulatory herbal supplements such as spirulina “may exacerbate pre-existing autoimmune disease or precipitate autoimmune disease in persons genetically predisposed to such disorders. Increased production of TNF-alpha may play a role, although more research is needed to clarify the mechanisms of such phenomena.”


Thank you very much for your assistance.


Dr. Braverman

2026 Posts
RE: Spirulina Posted on: Nov 15, 2012 at 5:56am
I have seen this , and am looking into it. I do beleive that the greens formulations in light of activated immune systems has to be reevaluated. I need more evidence, but I have gotten tot he point when I see resistance in immune parameters to start elimnating certain supplements. while they may not be the cause they might in fact exacerbate the activation. I will keep you posted.
Dr. Jeffrey Braverman MD FACOG
Medical Director
Braverman Reproductive Immunology P.C.


5 Posts
Reply RE: Spirulina Posted on: Nov 15, 2012 at 7:18am
Thank you very much for the speedy response.

I look forward to hearing more of your thoughts on this. In the meantime, it looks like my gorgeous spirulina has got to go...for now...:-(

Have a great week.

Kind regards,