positive SSB, positive ANA, and positive phosphatidylserine antibody (IGG)


2 Posts
Reply Posted on: Dec 30, 2015 at 7:09pm
Dear Dr. Braverman,

First of all I would like to say thank you for being one of the few reproductive immunologists out there helping women with immune issues get pregnant.

I saw a rheumatologist after finding that I have elevated Anti-Nuclear-Antibodies ( 1:140). It was found that I have positive SSB (Sjorgen's-related) and positive for one of the antiphospholipid antibodies, phosphatidylserine antibody (IGG) level was 21, which according to Quest says that range is a risk factor for miscarriage. I also have had a rash on my lower legs for the last two months, which i'll be getting biopsied tomorrow by a dermatologist to see if it's vasculitis ( I think that is related to Sjorgen's).

Do you think that I should be put on prednisone to help calm my immune system, before attempting IVF? I have read that it's best to get immune issues under control before attempting to get pregnant. Also, do you think that I should get put on Heparin or some kind of anticoagulant before trying to get pregnant, given I have a positive Phosphatidylserine Antibody (IGG) of 21? My rheumatologist doesn't seem to know what to do, as he usually doesn't treat women with immune issues trying to get pregnant. Is a blood thinner and prednisone protocol something you would consider given my info?

I have a phone consult scheduled with you, but am eager for any info I can get to help me solve my puzzle. Thanks so much for your help and wish you and your staff a very Happy New Year!

Dr. Braverman

2026 Posts
RE: positive SSB, positive ANA, and positive phosphatidylserine antibody (IGG) Posted on: Dec 31, 2015 at 9:57am
I think we should wait for the phone consult and I advise not to do any IVF until we speak and have a clear plan.
Braverman Medical Team
Braverman Reproductive Immunology P.C.