Hashimoto's and Genetic Carrier for x-linked condition

Hopeful33

3 Posts
Reply Posted on: Jun 2, 2013 at 12:36pm
Hi, I was diagnosed with Hashimoto's in March, 2013. I am currently on a 50 dose of Synthroid. I also learned a few months prior that I am genetic carrier for an x-linked condition (x-linked ichthyosis). We did IVF with Dr. Sher in Vegas and unfortunately had 2 chromosomally normal males at the end. We are unsure if they would have the condition I am a carrier of, so we are going to do a new IVF cycle again to try and get females.

My question...what, if anything can be done to increase the odds of getting more females? I saw that you have a sentence about this when you are describing your lab. I am 33 years old. Also, with this autoimmune condition, does this play into egg quality and follicle development?

I am calling your office to schedule an appointment with you. We live in Chicago.
Healthy baby girl born 12/31/11
Diagnosed with Hashimoto's in March 2013 and discovered I am a genetic carrier for an x-linked condition we are trying to avoid.

Dr. Braverman

2026 Posts
RE: Hashimoto's and Genetic Carrier for x-linked condition Posted on: Jun 3, 2013 at 6:21am
Cleary the autoimmune issues need to be addressed. There is no clear data yet on egg quality but there are studies that have found high levels of inflammatory cytokines in folliclar fluid and adversely affect egg quality .
There is no proven way to "increae" the odds of one gender over the other. Im not sure where you read that on our site.
I look forward to speaking with you.
Dr. Jeffrey Braverman MD FACOG
Medical Director
Braverman Reproductive Immunology P.C.

Hopeful33

3 Posts
Reply RE: Hashimoto's and Genetic Carrier for x-linked condition Posted on: Jun 3, 2013 at 8:42am
http://www.preventmiscarriage.com/In-Vitro-Fertilization-IVF-/Full-Service-IVF-Facility/Embryoplasty.aspx

Great. I have a phone call with you on 6/20 and have schedued an in person consult where I will travel to NY on 7/9. My last retrieval with Dr. Sher was on 5/16, so I think my body will be ready for the next run in July (with your approval of course).

Here is where the information is mentioned about the sperm and gender selection (click on link above). I also cut and pasted the information below for you. I know MicroSort went out of business and the FDA has not approved this as an option for patients who are in my situation, so I was surprised to see this.

What is your opinion about the density of the sperm and how that is more associated with a female? I have also read that X sperms are larger than Y sperm (X contain 2.8% more DNA than Y). Again, we are just trying to increase our odds, so if this is all bogus, then I guess we'll have to rely on luck. It was just so disappoionting to go through our last cycle and get only males at the end.

I also did do a pretty extensive immunology panel with Dr. Sher, but am wanting to speed up the process to get started with my next cycle with you. I realize that you may want to look at other things that could have been missed. I did receive your email address from your office, so I will email you my results in a bit. I want to make sure I can do all the tests you suggest prior to my consult with you on 6/20 so we are efficient as possible.

I REALLY appreciate your time and am looking forward to traveling to cycle with you in the near future. This past year has been just awful and we are ready to finally experience positive results.

Info from your website below...Highly Specialized Infertility Procedures


  • Sperm Sex Selection – Our sperm sex selection procedure is an option for patients who desire a specific gender, and who want to avoid genetic diseases that may afflict a specific gender.
  • High-Resolution Sperm Selection for ICSI – We use high-resolution and high-magnification microscopy in the selection of sperm that we use for ICSI in order to avoid sperm cells with certain abnormalities. This minimizes the probability of the resulting embryos being chromosomally abnormal.
Healthy baby girl born 12/31/11
Diagnosed with Hashimoto's in March 2013 and discovered I am a genetic carrier for an x-linked condition we are trying to avoid.

Dr. Braverman

2026 Posts
RE: Hashimoto's and Genetic Carrier for x-linked condition Posted on: Jun 3, 2013 at 8:45am
yes that is referring to microsort, Im not a fan , it is used for those that do not want to do IVF but still want an attempt at gender selection. This is not our procedure but sent to a lab that does the sorting, they do advertise high success , I have not seen that here in my clinic.
We can reveiw all of your testing when you come for your consult.
Dr. Jeffrey Braverman MD FACOG
Medical Director
Braverman Reproductive Immunology P.C.