NK Treatment

NK

2 Posts
Reply Posted on: Mar 29, 2013 at 5:17am
Dear Dr. Braverman,

first of all we would like to thank you for giving people all over the world the possibility to ask questions in this forum.

My wife and I are trying to conceive for about five years. During this time my wife only once got pregnant. A missed miscarriage happened after about ten weeks. I think it might be important to mention, that my wife had the flu and high fever at the time of conception. When she finally recovered the missed miscarriage happened. Since this time we received several ivf treatments without success. The course of infertility remains unclear. Recently we have had our blood tested on immunological matters. It turned out, that my wife has high levels of natural killer cells in the blood (CD3+CD16/56+: 424 µl (27 %)).

Now we are wondering, if pregnancy during the flu was not just a coincidence, but due to the immune system fighting the flue instead of keeping the fertilised egg from implantation.

We would love to hear your opinion on that matter and we would also be very thankful for your advice on further treatment. Our doctor recommended another ivf-cycle + granocyte.

Dr. Braverman

2026 Posts
RE: NK Treatment Posted on: Mar 29, 2013 at 6:18am
Treatment of the elevated NK cells is warranted, but you also have to be aware that this is just one of many immune paramters that must be looked at to correclty prescribe a treatment. I would be happy to guide you with his .
Dr. Jeffrey Braverman MD FACOG
Medical Director
Braverman Reproductive Immunology P.C.

NK

2 Posts
Reply RE: NK Treatment Posted on: Mar 29, 2013 at 7:51am
Dear Dr. Braverman,

thank you very much for the immediate response.

As we live in Europe, we unfortunately do not have the possibility to visit New York for further examination. But we do have an extensive blood report with lots of immunogenetic data (HLA typing, KIR typing, etc.). As far as we can see, only the elevated level of natural killer cells is remarkable.

Does granocyte have an effect on the killer cells or their activity?

Is there a way we can send the bloodreport to you for treatment recommendation via eMail and – if so – on what conditions?

Dr. Braverman

2026 Posts
RE: NK Treatment Posted on: Mar 29, 2013 at 8:09am
You can call or email our office and we can schedule a SKYPE or telephone consulatioins, if you email all of your results I will have them on hand for the consult , and I will be able to organize any other testing that we may need as well.
Dr. Jeffrey Braverman MD FACOG
Medical Director
Braverman Reproductive Immunology P.C.