Over active immune system


4 Posts
Reply Posted on: Mar 12, 2014 at 11:49am
Dear Dr. Braverman,
Im Danish, and undergoing fertility treatment in Denmark, starting my first IVF this month, a long protocol. Ive had 6 unsuccessful inseminations prior to this. 2 years ago I got pregnant the first time me and my ex tried but miscarried in week 9. The blood work they did during this my first pregnancy revealed low metabolism with 3-400 antibodies. Im now very well regulated on Eltroxin, my TSH is 1.4.
My fertility clinic knows about my low metabolism of course, but have never mentioned the possibility that I might have an over active immune system.
On my own initiative I had my testosterone tested 2 weeks ago, and got the answer today, my testosterone is 0.52 n/mol/L; My Dhea is within normal range but in the low end; However, the 'Sexualhormonbinding Globulin' is elevated at 180 where the normal range is 18-144.
Does this confirm my suspicion that I do have an overactive immune system?
Should I ask my clinic for Prednisolone? How early should one start the Prednisolone in an IVF treatment?
Thanks so much for your expertise and you generous help!
Yours Freya

Dr. Braverman

2026 Posts
RE: Over active immune system Posted on: Mar 12, 2014 at 9:07pm
You can not make a diagnosis of "over active " immune system based on this simple testing. The immune system is quite complex and extensive testing of the actual cells and markers in the immune system are necessary to reach this type of conclusion. We woudl be happy to assist you with this, simply fill out a consult request ont he website and we will be in touch.
Dr. Jeffrey Braverman MD FACOG
Medical Director
Braverman Reproductive Immunology P.C.