Pregnancy outcome and Coronavirus (COVID-19): What we know so far.

Posted By Braverman IVF & Reproductive Immunology || 19-March-2020

COVID-19 is a novel viral respiratory disease caused by a new strain of the coronavirus (SARS-COV-2), first identified in Wuhan, China.

This virus is transmitted from human to human, through respiratory, fomites or fecal matter.

In a study published today, the authors reported 4 full-term, singleton, healthy infants (COVID-19 negative) born from infected mothers that tested positive for COVID-19.
All four mothers were symptomatic for COVID-19 during their third trimester, with fever, cough, fatigue and/or headache.

Many samples were tested (neonatal throat swab, amniotic fluid, cord blood and breast milk) and all came back negative.

Clinical studied on pregnant women and COVID-19 are very limited.

Only one case of possible transmission of the virus from the mother to the fetus has been reported. In a study1, including nine pregnant women with symptomatic COVID-19 and who tested positive for the virus, the authors showed no vertical transmission (from the mother to the fetus) and all six infants tested were COVID-19 negative.

Based on clinical studies led in China, most pregnant women, positive for COVID-19 had only mild symptoms and only one study2 reported the case of a pregnant woman whose condition required ventilation. She had an emergency c-section but had a full recovery. There are no data on COVID-19 and increased risk for pregnancy loss or congenital malformations.

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We will be in touch with any further updates, stay safe!


1- Chen H, Guo J, Wang C, et al. Clinical characteristics and intrauterine vertical transmission potential of COVID-19 infection in nine pregnant women: a retrospective review of medical records. Lancet 2020.

2- Wang X, Zhou Z, Zhang J, et al. A case of 2019 Novel Coronavirus in a pregnant woman with preterm delivery. Clinical Infectious Diseases 2020.


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